Cardiac surgery associated with acute and chronic kidney damage
30 to 50 percent of patients undergoing surgery for congenital heart disease experience some form of cardiac-surgery associated acute kidney injury (CS-AKI), report nephrologists at the University of Cincinnati College of Medicine in Ohio (US). A similar association seems to be true for chronic kidney disease as well, as the present study showed.
The authors analyzed data from Danish population registries, including patients with congenital heart disease who were born between 1990 and 2010 and who underwent their first cardiac surgery before the age of 15 years. Median follow-up was almost five years.
The two main results:
Of 382 patients with congenital heart disease undergoing cardiac surgery, approximately one third (n=127) experienced CS-AKI within five days of surgery.
The five-year cumulative incidence of CKD for patients with CS-AKI was twelve percent and therefore four times as high as that for patients without CS-AKI (3 %; significant adjusted HR 3.8).
The authors’ conclusion: CS-AKI in patients with congenital heart disease is not only a common occurrence, but it is also associated with an increased risk for CKD.