The ANCA update

What is new regarding ANCA glomerulonephritis and vasculitis? Researchers at the University of North Carolina (US) give an overview based on current literature: Epidemiology and pathogenesis: ...

BMI identifies high-risk renal transplant patients

Body mass index (BMI) has a number of important associations for kidney transplant recipients (KTRs), say nephrologists at the University of Ferrara in Italy: For one, KTRs are bound to develop......

Cardiac surgery associated with acute and chronic kidney damage

30 to 50 percent of patients undergoing surgery for congenital heart disease experience some form of cardiac-surgery associated acute kidney injury (CS-AKI), report nephrologists at the University...

The ANCA update

What is new regarding ANCA glomerulonephritis and vasculitis? Researchers at the University of North Carolina (US) give an overview based on current literature: Epidemiology and pathogenesis: ...

BMI identifies high-risk renal transplant patients

Body mass index (BMI) has a number of important associations for kidney transplant recipients (KTRs), say nephrologists at the University of Ferrara in Italy: For one, KTRs are bound to develop......

Cardiac surgery associated with acute and chronic kidney damage

30 to 50 percent of patients undergoing surgery for congenital heart disease experience some form of cardiac-surgery associated acute kidney injury (CS-AKI), report nephrologists at the University...

eGFR and the risk of community-acquired infections

Community-acquired infections are common, associated with adverse outcomes and they therefore increase costs for the healthcare systems. An international team of researchers from renowned......

Hemodialysis: Early readmission associated with mortality

In the United States, readmission of patients with end-stage renal disease (ESRD) seems to be independently associated with a substantially increased risk of mortality, say researchers at the......

Biomarkers and kidney function in diabetes

Biomarkers of diverse pathophysiologic mechanisms could be used to improve the risk stratification for incident or progressive diabetic kidney disease (DKD) in persons with type 2 diabetes, say......

New way to estimate eGFR in cancer patients

Physicians treating cancer patients on carboplatin therapy need to know the glomerular filtration rate to adequately dose the patients. This can constitute a challenge, as there is not enough data...

Maintenance dialysis: Depression and poor social support drive readmission rates

Maintenance dialysis patients frequently need to be readmitted within 30 days. From prior studies, certain risk factors for readmission are already known, including comorbid conditions, laboratory...

Erythropoietin hyporesponsiveness in dialysis – and the role statins play

Should hemodialysis (HD) patients take statins or not? According to Japanese researchers at the Showa University in Tokyo, there is ample evidence to support lipid-lowering therapy with statins in...

Testosterone, males and mortality

In healthy men, low circulating testosterone levels are associated with higher risk of cardiovascular disease and death. For male patients on hemodialysis (HD), in whom testosterone deficiency is......

AKI: No matter how severe (or not), renal decline will follow

No matter how severe an episode of acute kidney injury is (AKI), and irrespective of proteinuria and post-episode function, it is always associated with increased subsequent renal decline; this......

Global cardiovascular and renal outcomes of reduced GFR

Chronic kidney disease is prevalent worldwide in the adult population. In the US and in Sub-Sahara Africa, approximately 13 percent of adults are thought to suffer from CKD, in Japan, the number......

CKD patients under pressure

J- or U-shaped: this is how the associations between blood pressure (BP) and mortality have previously been described in patients with chronic kidney disease (CKD). In the present study,......

Intradialytic cerebral ischemia: Frequent, unpredictable, significant

What is the relationship between blood pressure (BP) and downstream ischemia during hemodialysis (HD)? Researchers at Oxford University Hospitals NHS Trust instigated this pilot study to......

Fluid status, inflammation and their impact on survival

In dialysis patients, the presence of extracellular fluid overload (FO) is associated with hypertension and left ventricular hypertrophy, while reversal of FO improves blood pressure (BP) and......

Intradialytic hypertension: Pathophysiology and implications

Ten to 15 percent of hemodialysis (HD) patients regularly experience intradialytic hypertension. According to recent reports, intradialytic hypertension (of any magnitude) increases mortality risk...

(Kidney) size matters

The length of the kidney – often measured during routine abdominal ultrasonography – might help to identify patients at high (cardio)vascular and renal risk, say Dutch nephrologists at the......

Renal function and sodium intake: A review

Recent guidelines propose a dietary sodium intake of less than 2.0 g or even less than 1.5 g daily for patients with chronic kidney disease (CKD), report Japanese nephrologists at the Teikyo......

How urinary metabolites and genetics influence chronic kidney disease

Nephrologists at the Brigham and Women’s Hospital in Boston analyzed data of the Framingham Offspring Cohort. The aim: to determine the association between urinary metabolites, genetic variants,......

Higher ultrafiltration rate > longer dialysis recovery time

What is the association between ultrafiltration rate (UFR) and dialysis recovery time (DRT)? Fairly straightforward, as scientists at Stanford University in California discovered: A higher UFR is......

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