Maintenance dialysis: Depression and poor social support drive readmission rates

Maintenance dialysis patients frequently need to be readmitted within 30 days. From prior studies, certain risk factors for readmission are already known, including comorbid conditions, laboratory...

Erythropoietin hyporesponsiveness in dialysis – and the role statins play

Should hemodialysis (HD) patients take statins or not? According to Japanese researchers at the Showa University in Tokyo, there is ample evidence to support lipid-lowering therapy with statins in...

Testosterone, males and mortality

In healthy men, low circulating testosterone levels are associated with higher risk of cardiovascular disease and death. For male patients on hemodialysis (HD), in whom testosterone deficiency is......

Maintenance dialysis: Depression and poor social support drive readmission rates

Maintenance dialysis patients frequently need to be readmitted within 30 days. From prior studies, certain risk factors for readmission are already known, including comorbid conditions, laboratory...

Erythropoietin hyporesponsiveness in dialysis – and the role statins play

Should hemodialysis (HD) patients take statins or not? According to Japanese researchers at the Showa University in Tokyo, there is ample evidence to support lipid-lowering therapy with statins in...

Testosterone, males and mortality

In healthy men, low circulating testosterone levels are associated with higher risk of cardiovascular disease and death. For male patients on hemodialysis (HD), in whom testosterone deficiency is......

AKI: No matter how severe (or not), renal decline will follow

No matter how severe an episode of acute kidney injury is (AKI), and irrespective of proteinuria and post-episode function, it is always associated with increased subsequent renal decline; this......

Global cardiovascular and renal outcomes of reduced GFR

Chronic kidney disease is prevalent worldwide in the adult population. In the US and in Sub-Sahara Africa, approximately 13 percent of adults are thought to suffer from CKD, in Japan, the number......

CKD patients under pressure

J- or U-shaped: this is how the associations between blood pressure (BP) and mortality have previously been described in patients with chronic kidney disease (CKD). In the present study,......

Intradialytic cerebral ischemia: Frequent, unpredictable, significant

What is the relationship between blood pressure (BP) and downstream ischemia during hemodialysis (HD)? Researchers at Oxford University Hospitals NHS Trust instigated this pilot study to......

Fluid status, inflammation and their impact on survival

In dialysis patients, the presence of extracellular fluid overload (FO) is associated with hypertension and left ventricular hypertrophy, while reversal of FO improves blood pressure (BP) and......

Intradialytic hypertension: Pathophysiology and implications

Ten to 15 percent of hemodialysis (HD) patients regularly experience intradialytic hypertension. According to recent reports, intradialytic hypertension (of any magnitude) increases mortality risk...

(Kidney) size matters

The length of the kidney – often measured during routine abdominal ultrasonography – might help to identify patients at high (cardio)vascular and renal risk, say Dutch nephrologists at the......

Renal function and sodium intake: A review

Recent guidelines propose a dietary sodium intake of less than 2.0 g or even less than 1.5 g daily for patients with chronic kidney disease (CKD), report Japanese nephrologists at the Teikyo......

How urinary metabolites and genetics influence chronic kidney disease

Nephrologists at the Brigham and Women’s Hospital in Boston analyzed data of the Framingham Offspring Cohort. The aim: to determine the association between urinary metabolites, genetic variants,......

Higher ultrafiltration rate > longer dialysis recovery time

What is the association between ultrafiltration rate (UFR) and dialysis recovery time (DRT)? Fairly straightforward, as scientists at Stanford University in California discovered: A higher UFR is......

Diabetes with early kidney involvement: Loss of 16 years

16 years: This is the average amount of lifetime lost to patients with diabetes and early kidney involvement, say the authors of the present joint US-Taiwanese study. They identified the excess......

Compress to avoid intradialytic hypotension

Conventional hemodialysis (HD) is associated with dialysis-induced hypotension (DIH) and ineffective phosphate removal, say Brazilian nephrologists at the University São Paulo. Their approach to......

Management of hyperkalemia in CKD: Two new drugs

Patients with chronic kidney disease (CKD) face a well-known increased risk of hyperkalemia, associated with an increase in short- and long-term mortality. In the past, the disorder was mainly......

Improving dialysis access for elderly HD patients

When commencing hemodialysis (HD) in elderly patients, there are two factors to consider say scientists at New York’s Renal Research Institute: one, using a catheter is associated with a higher......

Phosphorus binders: Do they or don’t they improve mortality?

To date, there is no agreement whether the benefits of phosphorus binders extend to those without end stage renal disease, say nephrologists at the Kaiser Permanente Los Angeles Medical Center. In...

Hemodialysis: Age, access and mortality

In Japan and elsewhere, all hemodialysis (HD) patients are generally recommended to create a fistula first. However, creating a mature arteriovenous fistula (AVF) can be challenging in elderly......

Once upon a time: The story of erythropoetin and biosimilars

Anemia is the most common complication of advanced chronic kidney disease (CKD), and the decreased production of erythropoietin (EPO) is the main etiologic factor. The first recombinant human......

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